Calcium L-5-Methyltetrahydrofolate
Quality & Regulatory Documents
COA confirms batch purity and identity according to USP specifications. TDS provides formulation reference data. MSDS supports safety and handling information. Allergen and GMO statements are available for regulatory documentation.
Pharmacopoeia & Certificates
The product complies with the USP2024 standard and can be manufactured under GMP-compliant production systems suitable for nutraceutical and pharmaceutical ingredient supply chains.
Market & Certification Support
Halal and Kosher certificates can be provided for global supplement markets. Heavy metals reports, BSE/TSE statements, and origin declarations support regulatory submissions in the United States, Europe, and Asia-Pacific regions.
Product Overview
Calcium L-5-Methyltetrahydrofolate is the biologically active form of folate used as a functional ingredient in dietary supplement and nutrition formulations.
Also known as
L-5-MTHF Calcium, 5-Methyltetrahydrofolate Calcium Salt, Active Folate
Description
Calcium L-5-Methyltetrahydrofolate is the calcium salt of L-5-methyltetrahydrofolate, the metabolically active form of vitamin B9. Unlike synthetic folic acid, L-5-MTHF does not require enzymatic conversion by the MTHFR pathway, making it suitable for formulations targeting efficient folate bioavailability.
From a B2B ingredient perspective, Calcium L-5-Methyltetrahydrofolate is widely used in high-quality dietary supplements and prenatal formulations due to its stability, defined purity profile, and compatibility with modern nutritional formulations. The ingredient is typically supplied as a light yellow crystalline powder with controlled moisture content and validated purity according to pharmacopoeial standards.
Manufacturers prefer Calcium L-5-Methyltetrahydrofolate when developing advanced folate products designed for pregnancy nutrition, cognitive health, cardiovascular support, and methylation-related formulations.
Available Specifications
Calcium L-5-Methyltetrahydrofolate is available in pharmacopoeial-grade specifications aligned with USP standards, with high purity levels and controlled impurity profiles suitable for dietary supplement and functional nutrition manufacturing. The ingredient can be supplied in different particle sizes and stability-optimized forms depending on formulation requirements.
Applications
Dietary Supplements
Calcium L-5-Methyltetrahydrofolate can be used for active folate supplementation in capsule, tablet, and powder-blend dietary supplement formulations.
Functional Nutrition
Calcium L-5-Methyltetrahydrofolate can be used for methylation support and daily wellness formulations in functional nutrition products and fortified nutritional blends.
Sports / Active Nutrition
Calcium L-5-Methyltetrahydrofolate can be used for metabolic and cellular health support in advanced nutrition formulations targeting active lifestyles.
Pharmaceutical / Medical
Calcium L-5-Methyltetrahydrofolate can be used as a bioactive folate ingredient in pharmaceutical or medical nutrition formulations requiring pharmacopoeia-grade folate.
Typical Dosage Forms
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Hard capsules
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Tablets
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Powder blends
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Sachets
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Functional drink mixes
FAQ
What is Calcium L-5-Methyltetrahydrofolate?
Calcium L-5-Methyltetrahydrofolate is the biologically active form of folate used as an advanced vitamin B9 ingredient in nutritional formulations.
How is it different from folic acid?
Unlike folic acid, L-5-MTHF does not require enzymatic conversion and is directly utilized by the body as active folate.
What specification does this product follow?
This product complies with the USP2024 standard for Calcium L-5-Methyltetrahydrofolate.
Which formulations commonly use this ingredient?
It is widely used in prenatal supplements, methylation support products, and advanced multivitamin formulations.
How should the ingredient be stored?
The product should be stored in a cool, dry environment away from light and moisture to maintain stability.
Related Products
RFQ Readiness
Assay, mesh, purity, source, carrier, dosage form and target application.
COA, TDS, MSDS, allergen, Non-GMO, Halal, Kosher or market files when available.
Evaluation sample, pilot order, bulk quantity, shelf life and packing preference.
Destination country, carton/drum/pallet details, lead time and shipment coordination.